Can this be applied to osb board?

Great question! The Rust-Oleum Concrete and Garage Floor Paint won't adhere properly to wood. Instead, use the Rust-Oleum RockSolid Polycuramine Garage Floor Coating Kit, which is suitable for wood. Sand the wood instead of using the etching powder that is included in the kit. Coverage is less on wood, so we'd recommend going with the 2.5-car kit! We're happy to answer any other application questions you may have. Just call us at 888-683-5667! https://www.lowes.com/pd/Rust-Oleum-RockSolid-2-part-Dark-Gray-Gloss-Garage-Floor-Polycuramine-Kit-Actual-Net-Contents-152-fl-oz/1000201199 — Rust-Oleum Product Support 15